Exploring the economic impact of institutional entrepreneurship, social Innovation, and poverty reduction on carbon footprint in BRICS countries: what is the role of social enterprise?

The world is facing challenges to reduce carbon emissions, the complex interplay between socioeconomic dynamics and environmental sustainability is of utmost importance. In the context of the BRICS nations-Brazil, Russia, India, China, and South Africa-this study explores the intricate interactions between institutional entrepreneurship, institutional innovation, poverty reduction, social globalization, urbanization, and social entrepreneurship as well as their combined effects on the carbon footprint over the period of 1990 to 2021. This work examines the multi-dimensional interactions inside this nexus using a thorough analytical strategy that includes the Generalized Method of Moments (GMM), Three-Stage Least Squares (3SLS), and Robust regression approaches. Institutional entrepreneurship and innovation are the main forces behind institutional change and may have an impact on how people behave in terms of the environment. Strategies for reducing poverty frequently involve greater resource usage, which has an impact on carbon footprint. Examining social globalization's impact on carbon footprints is necessary given how it affects consumer habits and economic activity. Rapid urbanization is a dual problem because it spurs both increased energy demand and novel sustainability measures. With its emphasis on community-driven solutions, social entrepreneurship can provide regional solutions to reduce poverty and carbon emissions. The study's findings provide policymakers, practitioners, and researchers with insights into the complex web of socio-economic factors that underlies carbon footprint fluctuations. This research paves the way for informed policy decisions, sustainable business practices, and the pursuit of harmonious development that addresses both economic aspirations and environmental imperatives within the BRICS countries by illuminating the connections between institutional entrepreneurship, innovation, poverty reduction, social globalization, urbanization, social entrepreneurship, and carbon emissions.

Inorganic novel cubic halide perovskite Sr3AsI3: Strain-activated electronic and optical properties.

In recent years, inorganic perovskite materials have attracted a lot of attention in the field of solar technology due to their exceptional structural, optical, and electronic properties. This study thoroughly investigated, using first-principles density-functional theory (FP-DFT), the impact of compressive and tensile strain on the structural, optical, and electrical properties of the inorganic cubic perovskite Sr3AsI3. The unstrained planar Sr3AsI3 molecule exhibits a direct bandgap of 1.265 eV value at Γ point. The bandgap of the Sr3AsI3 perovskite is lowered to 1.212 eV when the relativistic spin-orbital coupling (SOC) effect is subjected in the observations. In addition, the structure's bandgap exhibits a falling prevalence due to compressive strain and a slight rise due to tensile strain. The optical indicators such as dielectric functions, absorption coefficient, reflectivity, and electron loss function show that this component has a great ability to absorb in the visible range in accordance with band characteristics. When compressive strain is raised, it is discovered that the spikes of the dielectric constant of Sr3AsI3 move to lower photon energy (redshift), and conversely, while growing tensile strain, it exhibits increased photon energy changing behavior (blueshift). As a result, the Sr3AsI3 perovskite is regarded as being ideal for use in solar cells for the production of electricity and light management.

UBL3 Interaction with α-Synuclein Is Downregulated by Silencing MGST3.

Ubiquitin-like 3 (UBL3) is a membrane-anchored protein that plays a crucial role in sorting proteins into small extracellular vesicles. Aggregations of alpha-synuclein (α-syn) are associated with the pathology of neurodegenerative diseases such as Parkinson's disease. Recently, the interaction between UBL3 and α-syn was discovered, with potential implications in clearing excess α-syn from neurons and its role in disease spread. However, the regulator that can mediate the interaction between UBL3 and α-syn remains unclear. In this study, using the split gaussian luciferase complementation assay and RNA interference technology, we identified that QSOX2, HTATIP2, UBE3C, MGST3, NSF, HECTD1, SAE1, and ATG3 were involved in downregulating the interaction between UBL3 and α-syn. Notably, silencing MGST3 had the most significant impact. Immunocytochemistry staining confirmed the impact of MGST3 silencing on the co-localization of UBL3 and α-syn in cells. MGST3 is a part of the antioxidant system, and silencing MGST3 is believed to contribute to oxidative stress. We induced oxidative stress with hydrogen peroxide, observing its effect on the UBL3-α-syn interaction, and showing that 800 µM of H2O2 downregulated this interaction. In conclusion, silencing MGST3 downregulates the interaction between UBL3 and α-syn.

Tailoring the microstructure of BiVO4 sensing electrode by nanoparticle decoration and its effect on hazardous NH3 sensing.

Real-time monitoring and quantification of exhaust pollutants is crucial but is troublesome because of extremely harsh thermochemical conditions, and in this regard mixed-potential sensing technology can be a realistic solution. In this study, BiVO4 nanoparticles are decorated onto the preformed porous sensing electrode (SE) backbone by homogeneous infiltration process to improve the sensing performance in mixed-potential sensor. The influence of nanoparticle decoration on phase composition, microstructure and sensing performance are analyzed by physical and electrochemical techniques. Corresponding results indicate that the microstructure tailoring enhances the sensor performance, by extending the triple phase boundary (TPB) and surface area of SE itself. The sensitivity (-119.47 mV/decade) and response time (20 s) of i-BVO SE-based sensor at 600 â„ƒ are 20 % higher and 8 s faster than bare BiVO4 SE-based sensor (99.24 mV/decade and 28 s). Additionally, the i-BVOǀYSZǀPt cell exhibits good selectivity and cross-sensitivity toward NH3 without any dependency on oxygen partial pressure (pO2). The fabricated sensor is also found stable towards cyclic and long-term operations. Electrochemical Impendence Spectroscopy (EIS) and DC polarization studies were performed to confirm the mixed-potential behavior. Conclusively, the superior sensing performance of i-BVO SE compared to various oxide based SEs highlights its suitability for mixed-potential NH3 sensing.

The protective and antioxidant effects of Hygrophila schulli seeds on oxidative damage of DNA and RBC cellular membrane.

Medicinal plants are sources of antioxidant which may protect the body against oxidative stress related diseases and can be used as human food supplements. In this investigation, seeds of Hygrophila schulli (M. R. Almeida & S. M. Almeida) (Fam.-Acanthaceae), a herbaceous plant well known for its medicinal properties, has been examined for antioxidant activity of crude methanolic extract (CME) and its fraction using in vitro and in vivo assay as well as their protective activity against oxidative damage of DNA and RBC. Total phenolic and flavonoid content have also been estimated using the aluminum chloride colorimetric and Folin-Ciocalteu method. Among the different fractions of CME, Ethyl acetate fraction (EAF) had higher antioxidant activity in vitro assay and was selected for in vivo antioxidant activity in cadmium intoxicated mice. The EAF showed a significant (p < 0.05) increase in serum catalase and SOD activity compared to the control group. TBARS levels were restored to 17.42 and 19.19 nmol/mg protein, respectively, after treatment with EAF and standard ascorbic acid (AA); compared to the normal group (14.96 nmol/mg protein). Similarly, levels of albumin, bilirubin, uric acid, and alkaline phosphatase were also brought back to normal levels. EAF's protective role against oxidative damage of DNA has shown a significant reduction in destroying of nicked DNA. RBC as a target of oxidation by H2O2 and HOCl, EAF showed inhibition of oxidation in a concentration-dependent manner, compared to standard gallic acid. In this study, we confirmed that EAF could scavenge reactive oxygen species (ROS) thus preventing DNA strand scission and the extract can be used as a functional food or nutraceutical product for health benefits.